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Early data also suggest potential benefits in liver disease, obstructive sleep apnea, chronic respiratory disorders, neurodegenerative and psychiatric conditions, reproductive dysfunction, obesity-associated cancers, and sepsis, although these remain investigational
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Moreover, evidence supporting EGCGs neuroprotective effects via BBB-mediated anti-neuroinflammation and reduction of oxidative stress includes: (i) EGCG enhances dopamine neuron activity in the gut, decreases serotonin levels in the colon, and increases hippocampal 5-hydroxytryptamine levels by enhancing intestinal permeability (215217)
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